Tags

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  • A set of published rules/criteria that define when tumours in cancer patients improve (respond), stay the same (stabilise) or worsen (progress) during treatments.
  • Published in Feb 2000 (updated in 2009) by an international collaboration including
    • European Organisation for Research & Treatment of Cancer (EORTC)
    • National Cancer Institute of the United States
    • National Cancer Institute of Canada Clinical Trials Group
  • Today, the majority of clinical trials evaluation cancer treatments for objective response in solid tumours are using RECIST
  • Specifically not meant to determine whether patients have improved or not, as these are tumour-centric, not patient centric criteria
    • It is not intended that these RECIST guidelines play a role in that decision making, except if determined appropriate by the treating oncologist
  • Can be used with CT, MRI or conventional radiography
  • Characterise lesions as measurable or non-measurable & target vs non-target